Factor XI

 

Factor XI - HemopHILIA C

Factor XI deficiency is an inherited bleeding disorder that is caused by a problem with factor XI. Either the body produces less factor XI than it should or because the factor XI is not working properly; the clotting reaction is blocked prematurely and the blood clot does not form.

Factor XI deficiency is also called hemophilia C. Factor XI differs from hemophilia A or B in that there is no bleeding into joints and muscles. Factor XI deficiency is the most common of the rare bleeding disorders and the second most common bleeding disorder affecting women (after von Willebrand disease).

Some people have inherited factor XI deficiency when only one parent carries the gene. The disorder is most common among Jews of Eastern European ancestry.